ABSTRACT
Background: Intrauterine insemination (IUI) remains an inexpensive, non-invasive, and effective first-line artificial insemination technique. The technique of IUI has evolved through various innovations since the time Cohen published the first report of IUI in 1962, and the success rate increased from 5% to >20%. The success of IUI depends upon several factors; two such prognostic factors are the timing and frequency of insemination. The objective of this study was to compare the effectiveness of single versus double intrauterine insemination.Methods: This prospective randomized study was carried out in 130 patients with male factor infertility, PCOS and unexplained infertility. Patients were randomly assigned into two groups. In the first group of 65 patients, single IUI was applied at 36 to 40 hours after HCG administration, to the other 65 patients in the second group, double IUIs were applied at 12 to 16 hours and 36 to 40 hours after HCG administration. The primary end-point of the study was to compare the clinical pregnancy rate between the two groups.Results: The overall pregnancy rate was 18.46% (12/65) for single IUI group and 30.76% (20/65) for double IUI group. There was a no statistically significant difference between single and double IUI groups (p=0.16).Conclusions: This study did find a higher pregnancy rate following double IUI; however, the difference was not statistically significant. Further, larger sample size studies are required to determine if double IUI increases the pregnancy rate.
ABSTRACT
Background: Diabetes mellitus (DM) is a rapidly growing health problem in India. Diet and physical activity are important modifiable risk factors affecting the incidence, severity and management of DM. The aim of the study was to assess diet of diabetes mellitus patients. 87 adults from a cohort of diabetic patients attending the Medical Clinics at the Hamidia Hospital Bhopal were invited for the study.Methods: Information about their nutritional status & food consumption pattern was taken by 24-hour dietary recall and food frequency questionnaire. Data was analysed using Epi Info and MS Excel. Frequency counts and percentages were used to describe the demographic characteristics of the participants while the significance difference in between male and female participants. The significance level was set at P <0.05 and 0.01. Statistical analysis used: MS Excel and Epi Info.Results: The study sample was 87 out of which 56 were females and 31 were males; mean age of DM patients was 48.21±12.98.The mean energy intake was 1386.52 kcal and 1125.79 kcal among male and female. The mean protein intake was 68.71 g and 50.50 among male and female diabetics. There was significant difference between male and female age. There were no significant difference in body mass index and waist hip ratio between male and female. 30 (34.5%) & 16 (18.4%) were overweight and obese respectively.Conclusions: Based on these findings, the dietary practices of diabetic patients are inadequate and require improvement. Education and counselling about diet of a diabetes patient is needed.